HBG1
| {{#if: | | HBG1 }} | |||||||||||||
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| Struktur des HBG1-Proteins | |||||||||||||
| Andere Namen |
{{{Andere Namen}}} }} | ||||||||||||
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Vorhandene Strukturdaten: }} | |||||||||||||
| Eigenschaften des menschlichen Proteins
}} | |||||||||||||
| Masse/Länge Primärstruktur |
}} | ||||||||||||
| Sekundär- bis Quartärstruktur |
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| Kofaktor |
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| Präkursor |
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| Isoformen |
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| Bezeichner | |||||||||||||
| {{#if:HBGA, HBGR, HSGGL1 | Gen-Namen | Gen-Name}} | Gen-Name(n) }} | {{#if: | HBG1 | HBG1}}{{#if:HBGA, HBGR, HSGGL1 |, HBGA, HBGR, HSGGL1}} }} | ||||||||||||
| Externe IDs |
{{#if: |
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| Arzneistoffangaben | |||||||||||||
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| TCDB | {{{TCDB}}}
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| Bezeichnung | {{{TranspText}}}
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| EC, Kategorie | {{#if:| {{{EC-Nummer}}}}}{{#if: |, [[{{{Kategorie}}}]]}} }} | ||||||||||||
| MEROPS | {{{Peptidase_fam}}}}} | ||||||||||||
| MEROPS | {{{Inhibitor_fam}}}}} | ||||||||||||
| Reaktionsart | {{{Reaktionsart}}}
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| Substrat | {{{Substrat}}}
}} | ||||||||||||
| Produkte | {{{Produkte}}}
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}} | ||||||||||||
| Vorkommen | |||||||||||||
| {{#if: | [ {{#if: | Hovergen}}] | [http://hogenom.univ-lyon1.fr/query_sequence?seq= {{#if: | Hovergen}}]}} }} }} | |||||||||
| }} | |||||||||||||
| }}
}} | |||||||||||||
{{#if:Protein HBG1 PDB 1fdh.png||}}
Die Untereinheit Hemoglobin gamma-1 ist ein Protein, für welches das beim Menschen vorhandene HBG1-Gen codiert.<ref name="pmid2649166">{{#invoke:Vorlage:Literatur|f}}{{#if:
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Funktion
Die gammaglobin-Gene (HBG1 und HBG2) äußern sich normalerweise in der fötalen Leber, Milz und Knochenmark. Zwei gamma-Ketten bilden zusammen mit zwei alpha-Ketten das fötale Hämoglobin (HbF), welches bei der Geburt normalerweise durch das Hämoglobin Erwachsener (HbA) ersetzt wird. Bei einigen beta-Thalassämien und den damit verbundenen Bedingungen dauert die Produktion von gamma-Ketten auch noch im Erwachsenenalter an. Die zwei Arten von gamma-Ketten unterscheiden sich bei Residuum 136, wo man bei der G-gamma-Produktion (HBG2) Glycin und bei der A-gamma-Produktion (HBG1) Alanin vorfindet. Ersteres ist bei der Geburt prädominant. Die Reihenfolge der Gene im beta-globin Cluster lautet: 5' - ε – γ-G – γ-A – δ – β - 3'.<ref>{{#if:Vorlage:Cite book/URL|{{#iferror: {{#iferror:{{#invoke:Vorlage:FormatDate|Execute}}|}}| |}}}}{{#if:{{#if:
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|0|=Vorlage:Toter Link/Core{{#if: https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 | {{#if: | [2] }} (Seite {{#switch:|no|0|=|dauerhaft }}nicht mehr abrufbar{{#if: | , festgestellt im {{#invoke:DateTime|format||F Y}} }}. Suche im Internet Archive ){{#if: | {{#if: deadurlausgeblendet | | Vorlage:Toter Link/archivebot }} }} | (Seite {{#switch:|no|0|=|#default=dauerhaft }}nicht mehr abrufbar{{#if: | , festgestellt im {{#invoke:DateTime|format||F Y}} }}.) }}{{#switch: |no|0|= |#default={{#if: || }} }}{{#invoke:TemplatePar|check |opt = inline= url= text= datum= date= archivebot= bot= botlauf= fix-attempted= checked= |cat = Wikipedia:Vorlagenfehler/Vorlage:Toter Link |errNS = 0 |template = Vorlage:Toter Link |format = |preview = 1 }}{{#if: https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 | {{#if:{{#invoke:URLutil|isWebURL|https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047}} || {{#if: || }} }} | {{#if: | {{#if: || }} | {{#if: || }} }} }}{{#if: | {{#if:{{#invoke:DateTime|format||F Y|noerror=1}} || {{#if: || }} }} }}{{#switch: deadurl |checked|deadurl|= |#default= {{#if: || }} }}|#default= https://wiki-de.moshellshocker.dns64.de/index.php?title=Wikipedia:Defekte_Weblinks&dwl=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 Die nachstehende Seite ist {{#switch:|no|0|=|dauerhaft }}nicht mehr abrufbar]{{#if: | , festgestellt im {{#invoke:DateTime|format||F Y}} }}. (Suche im Internet Archive. ) {{#if: | {{#if: deadurlausgeblendet | | Vorlage:Toter Link/archivebot }} }}Vorlage:Toter Link/Core{{#switch: |no|0|= |#default= {{#if: || }} }}{{#invoke:TemplatePar|check |all = inline= url= |opt = datum= date= archivebot= bot= botlauf= fix-attempted= checked= |cat = Wikipedia:Vorlagenfehler/Vorlage:Toter Link |errNS = 0 |template = Vorlage:Toter Link |format = |preview = 1 }}{{#if: https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 | {{#if:{{#invoke:URLutil|isWebURL|https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047}} || {{#if: || }} }} }}{{#if: | {{#if:{{#invoke:DateTime|format||F Y|noerror=1}} || {{#if: || }} }} }}{{#switch: deadurl |checked|deadurl|= |#default= {{#if: || }} }}[https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 }}|{{#switch: |0|=Vorlage:Toter Link/Core{{#if: https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 | {{#if: | [3] }} (Seite {{#switch:|no|0|=|dauerhaft }}nicht mehr abrufbar{{#if: | , festgestellt im {{#invoke:DateTime|format||F Y}} }}. Suche im Internet Archive ){{#if: | {{#if: | | Vorlage:Toter Link/archivebot }} }} | (Seite {{#switch:|no|0|=|#default=dauerhaft }}nicht mehr abrufbar{{#if: | , festgestellt im {{#invoke:DateTime|format||F Y}} }}.) }}{{#switch: |no|0|= |#default={{#if: || }} }}{{#invoke:TemplatePar|check |opt = inline= url= text= datum= date= archivebot= bot= botlauf= fix-attempted= checked= |cat = Wikipedia:Vorlagenfehler/Vorlage:Toter Link |errNS = 0 |template = Vorlage:Toter Link |format = |preview = 1 }}{{#if: https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 | {{#if:{{#invoke:URLutil|isWebURL|https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047}} || {{#if: || }} }} | {{#if: | {{#if: || }} | {{#if: || }} }} }}{{#if: | {{#if:{{#invoke:DateTime|format||F Y|noerror=1}} || {{#if: || }} }} }}{{#switch: |checked|deadurl|= |#default= {{#if: || }} }}|#default= https://wiki-de.moshellshocker.dns64.de/index.php?title=Wikipedia:Defekte_Weblinks&dwl=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 Die nachstehende Seite ist {{#switch:|no|0|=|dauerhaft }}nicht mehr abrufbar]{{#if: | , festgestellt im {{#invoke:DateTime|format||F Y}} }}. (Suche im Internet Archive. ) {{#if: | {{#if: | | Vorlage:Toter Link/archivebot }} }}Vorlage:Toter Link/Core{{#switch: |no|0|= |#default= {{#if: || }} }}{{#invoke:TemplatePar|check |all = inline= url= |opt = datum= date= archivebot= bot= botlauf= fix-attempted= checked= |cat = Wikipedia:Vorlagenfehler/Vorlage:Toter Link |errNS = 0 |template = Vorlage:Toter Link |format = |preview = 1 }}{{#if: https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 | {{#if:{{#invoke:URLutil|isWebURL|https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047}} || {{#if: || }} }} }}{{#if: | {{#if:{{#invoke:DateTime|format||F Y|noerror=1}} || {{#if: || }} }} }}{{#switch: |checked|deadurl|= |#default= {{#if: || }} }}[https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3047 }} }}}}}}}}}}{{#if:| {{#invoke:Vorlage:Internetquelle|archivBot|stamp=|text={{#if:Vorlage:Cite book/URL|Vorlage:Webarchiv/archiv-bot}}
}}}}{{#invoke:TemplatePar|check |all= url= titel= |opt= autor= hrsg= format= sprache= titelerg= werk= seiten= datum= abruf= zugriff= abruf-verborgen= archiv-url= archiv-datum= archiv-bot= kommentar= zitat= AT= CH= offline= |cat= {{#ifeq: 0 | 0 | Wikipedia:Vorlagenfehler/Vorlage:Internetquelle}} |template= Vorlage:Internetquelle |format=0 |preview=1 }}{{#invoke:TemplatePar|check
|all = url= title= |opt = script-title= trans-title= archive-url= archiveurl= archive-date= archivedate= authors= vauthors= author= author1= authorlink= authorlink1= author-link= author-link1= author2= author-link2= author3= author-link3= author4= author-link4= author5= author-link5= author6= author7= author8= author9= last= first= last1= first1= last2= first2= last3= first3= last4= first4= last5= first5= last6= first6= last7= first7= last8= first8= last9= first9= others= language= lang= format= website= work= publisher= via= pages= page= at= date= year= id= bibcode= doi= pmid= pmc= arxiv= archivedate= archive-date= archivebot= accessdate= access-date= quote= comment= url-status= ref= url-access= orig-year= editor= editor-link= editor-last= editor-first= editor1-link= editor1-last= editor1-first= editor2= editor2-last= editor2-first= editor2-link= department= series= agency= location= place= publication-place= publication-date= type= asin= doi-broken-date= isbn= issn= jfm= jstor= lccn= mr= oclc= ol= osti= rfc= ssrn= zbl= postscript= df= mode= display-authors= display-editors= book-title= contribution-url= offline= coauthors= month= authorlink2= authorlink3= authorlink4= authorlink5= last10= first10= last11= first11= last12= first12= last13= first13= last14= first14= last15= first15= last16= first16= last17= first17= last18= first18= last19= first19= last20= first20= last21= first21= |cat = Wikipedia:Vorlagenfehler/Vorlage:Cite web |errNS = 0 |template = Vorlage:Cite web |format = |preview = 1 }}Vorlage:Cite book/URL{{#if: Vorlage:Cite book/Webarchiv | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}Vorlage:Cite book/Meldung2{{#if: Vorlage:Cite book/ParamBool | Vorlage:Cite book/Meldung }}{{#if: Vorlage:Cite book/ParamBool | Vorlage:Cite book/Meldung }}{{#if: Vorlage:Cite book/ParamBool | Vorlage:Cite book/Meldung }}{{#if: Vorlage:Cite book/ParamBool | Vorlage:Cite book/Meldung }}{{#if: Vorlage:Cite book/ParamBool | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}}{{#ifeq:^^|^^||+1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}}{{#ifeq:^^|^^||+1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:2012-05-19|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:en|^^|0|1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}{{#ifexpr: {{#ifeq:^^|^^|0|1}}{{#ifeq:^^|^^||+1}} > 1 | Vorlage:Cite book/Meldung }}</ref>
Einzelnachweise
<references></references>
Literatur
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Hemoglobin
|| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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}}Vorlage:Cite book/Meldung2{{#ifexpr: 0{{#ifeq:^^|^^||+1}}{{#ifeq:^^|^^||+1}}{{#ifeq:Huisman TH, Kutlar F, Gu LH|^^||+1}}{{#ifeq:^^|^^||+1}} > 1
| Vorlage:Cite book/Meldung
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Prog. Clin. Biol. Res.
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| Vorlage:Cite book/Meldung
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|| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Nucleic Acids Research.
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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| Vorlage:Cite book/Meldung
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Acta Haematol.
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Nature
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| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}{{#invoke:TemplatePar|check
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: J. Biol. Chem.
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: J. Mol. Biol.
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| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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}}{{#if: Vorlage:Cite book/ParamBool
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}{{#invoke:TemplatePar|check
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Biochim. Biophys. Acta
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| Vorlage:Cite book/Meldung
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| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Am. J. Hematol.
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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| Vorlage:Cite book/Meldung
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| Vorlage:Toter Link/archivebot
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}}{{#invoke:TemplatePar|check
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}}Vorlage:Cite book/URL{{#if: | Vorlage:Cite book/Meldung }}{{#if: | Vorlage:Cite book/Meldung }}{{#if: Mol. Phylogenet. Evol.
|| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
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}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}{{#if: Vorlage:Cite book/ParamBool
| Vorlage:Cite book/Meldung
}}Vorlage:Cite book/Meldung2{{#ifexpr: 0{{#ifeq:^^|^^||+1}}{{#ifeq:^^|^^||+1}}{{#ifeq:Bailey WJ, Hayasaka K, Skinner CG, et al.|^^||+1}}{{#ifeq:^^|^^||+1}} > 1
| Vorlage:Cite book/Meldung
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- Seiten mit defekten Dateilinks
- Wikipedia:Unbekannter Wert (Chemie)
- Wikipedia:Artikel ohne Wikidata-Datenobjekt (Chemie)
- Wikipedia:Proteinbild nicht vorhanden
- Wikipedia:Vorlagenfehler/Parameter:URL
- Wikipedia:Vorlagenfehler/Parameter:Linktext
- Wikipedia:Vorlagenfehler/Parameter:Datum
- Wikipedia:Vorlagenfehler/Vorlage:"
- Wikipedia:Weblink offline fix-attempted
- Wikipedia:Vorlagenfehler/Vorlage:Toter Link
- Wikipedia:Vorlagenfehler/Vorlage:Toter Link/URL fehlt
- Sauerstofftransporter
- Blutbestandteil
- Codiert auf Chromosom 11 (Mensch)